Inxtify (was Up) is a feature-rich Instagram client and uploader for OS X. Drag, drop, upload, and have fun.

Features

• Simple upload of images and videos by drag-and-drop
• Geo-tagging
• Change your profile picture
• Toggle private account setting
• Multiple Instagram accounts
• Schedule uploading
• Comment managing.
• Supported formats:
• Any image format that is natively viewable by OS X, including PSD!
• H.264 (MP4/MOV/M4V) videos