Image SXM is a version of the public domain image analysis software NIH Image that has been extended to handle the loading, display and analysis of scanning microscope images. Image SXM supports SAM, SCM, SEM, SFM, SLM, SNOM, SPM and STM images from the following systems:

• Asylum Research MFP-3D
• Burleigh Instruments
• DI NanoScope II
• DI NanoScope III
• DI NanoScope IV
• DME Rasterscope
• DME Surface Data File
• Gatan DigitalMicrograph
• JEOL JSM
• JEOL WinSem
• JEOL WinSPM
• JPK Instruments
• Klocke Nanotechnik Atomikro
• Leica LIF
• Leica TCS
• Molecular Imaging PicoScan
• NanoMagnetics Instruments SPMSIF
• Nanonics Imaging
• Nanonis
• Nanosurf easyScan
• Nanotec Electronica WSxM
• Noran Instruments Vantage
• NT-MDT
• Omicron Vakuumphysik
• Omicron SCALA
• Omicron Matrix
• Oxford Instruments TOPSystem
• Park Scientific Instruments HFS-LIF
• Park Scientific Instruments HDF
• Philips SEM
• Quesant Instruments
• RHK Technology SPM-32
• RHK Technology XPMPro
• Seiko Instruments (SIINT) SPI
• SPECS STM Aarhus
• ThermoMicroscopes
• TopoMetrix SPMLab
• Unisoku
• Vacuum Generators SAM
• Veeco Innova
• WA Technology
• WA Technology TOPSystem
• Zeiss AxioVision
• Zeiss LSM

In addition, the following non-SXM file formats are also supported:

• AVI
• Bio-Rad
• BMP
• FITS
• Hamamatsu Image Seq
• Nikon NEF
• Omicron SPA-LEED
• PDSF
• PDSS
• Pentax PEF
• Philips APD
• SBIG CCD
• SPEC
• Targa TGA
• UBM
• Wyko OPD