0xED is a native OS X hex editor based on the Cocoa framework.

Features:

• Fast editing of large files
• Unlimited file size (limited by what the actual file system supports)
• Small memory footprint
• Instant opening of files of any size
• Remains responsive with 1 million+ edits
• Supports all normal text editor keyboard shortcuts
• HFS+ compatible
• Full hex/text search/replace
• Binary/text Cut/copy/paste support
• Main window is sizable
• Plug-in system to display your custom data types
• Intel 32/64 bit binary
• Localizations available: Italian, French, German, Simplified Chinese
• Free of charge
• PowerPC and 10.3/10.4/10.5 builds are available